Paschim Vihar, Delhi
GST No. 07AOFPC0081E1ZK
Approx. Rs 450 / BoxGet Latest Price
Product BrochureProduct Details:Packaging Size | 1x10 tablets |
Brand | Capget |
Composition | Capecitabine |
Manufacturer | GLS |
Treatment | Cancer Treatment |
Prescription/Non prescription | Prescription |
Form | Tablet |
Strength | 500 mg |
Approx. Rs 450 / BoxGet Latest Price
Product BrochureProduct Details:Packaging Size | 1x10 Tablet/Blister |
Brand | Naprocap |
Composition | Capecitabine |
Manufacturer | Miracalus |
Treatment | Cancer Treatment |
Prescription/Non prescription | Prescription |
Form | Tablet |
Strength | 500 mg |
Approx. Rs 400 / BoxGet Latest Price
Product BrochureProduct Details:Packaging Size | 10x10 Tablet |
Brand | Cacit |
Composition | Capecitabine |
Manufacturer | Zydus |
Treatment | Cancer of colon and rectum |
Prescription/Non prescription | Prescription |
Form | Tablet |
Strength | 500 mg |
Approx. Rs 400 / BoxGet Latest Price
Product BrochureProduct Details:Packaging Size | 10 Tablets/Box |
Brand | Capegard |
Composition | Capecitabine |
Manufacturer | Cipla |
Treatment | Breast Cancer |
Prescription/Non prescription | Prescription |
Strength | 500 mg |
Capecitabine is a non-cytotoxic fluoropyrimidine carbamate, which functions as an orally administered precursor of the cytotoxic moiety 5-fluorouracil (5-FU). Capecitabine is activated via several enzymatic steps. The enzyme involved in the final conversion to 5-FU, thymidine phosphorylase, is found in tumour tissues, but also in normal tissues, albeit usually at lower levels. In human cancer xenograft models, capecitabine demonstrated a synergistic effect in combination with docetaxel, which may be related to the upregulation of thymidine phosphorylase by docetaxel.
Enzymes convert capecitabine to 5-FU in vivo. Both normal and tumour cells metabolize 5-FU to 5-fluoro-2'-deoxyuridine monophosphate (FdUMP) and 5-fluorouridine triphosphate (FUTP). These metabolites cause cell injury by two different mechanisms. Firstly, FdUMP and the folate cofactor, N5-10-methylenetetrahydrofolate, bind to thymidylate synthase (TS) to form a covalently-bound ternary complex. This binding inhibits the formation of thymidylate from 2'-deoxyuridylate. Thymidylate is the necessary precursor of thymidine triphosphate, which is essential for the synthesis of DNA, so that a deficiency of this compound can inhibit cell division. Secondly, nuclear transcriptional enzymes can mistakenly incorporate FUTP in place of uridine triphosphate (UTP) during the synthesis of RNA. This metabolic error can interfere with RNA processing and protein synthesis. Since DNA and RNA are essential for cell division and growth, the effect of 5-FU may be to create a thymidine deficiency that provokes unbalanced growth and death of a cell. The effects of DNA and RNA deprivation are most marked on those cells that proliferate more rapidly and metabolize 5-FU at a more rapid rate.
Approx. Rs 550 / BoxGet Latest Price
Product BrochureProduct Details:Packaging Size | 1x10 Tablets/Box |
Brand | Xecap |
Composition | Capecitabine |
Manufacturer | RPG Life Sciences |
Treatment | Breast Cancer |
Prescription/Non prescription | Prescription |
Form | Tablet |
Strength | 500 mg |
Approx. Rs 350 / BoxGet Latest Price
Product BrochureProduct Details:Packaging Size | 3x10 Tablets/Box |
Brand | Capsy |
Composition | Capecitabine |
Manufacturer | Intas |
Treatment | Breast Cancer |
Prescription/Non prescription | Prescription |
Form | Tablet |
Strength | 500 mg |
Approx. Rs 450 / BoxGet Latest Price
Product BrochureProduct Details:Packaging Size | 10 Tablet/Box |
Brand | Relicitabine |
Composition | Capecitabine |
Manufacturer | Reliance Life Insurance |
Treatment | Breast Cancer,Cancer of colon and rectum |
Prescription/Non prescription | Prescription |
Form | Tablet |
Dose Strength | 500 mg |
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